Rex MD vs Sesame
Rex MD scores higher overall (9.1 vs 8.5).
By Julian Caraulani · prices checked
Quick verdict
Our pick between the two: Rex MD
Rex MD scores 9.1/10 against 8.5 for Sesame, ahead on price, price transparency, access and reputation. Sesame can still be the better fit: it is best for men who want a prescription from a clinician they pick and are happy to fill it at a pharmacy.
Side by side
| Rex MD | Sesame | |
|---|---|---|
| Lowest price | $18/mo (reduced price with a 6-month order) | Not published |
| Our score | 9.1/10 | 8.5/10 |
| Treatments | Erectile dysfunction (ED), Hair loss, Premature ejaculation (PE), Low testosterone (TRT and enclomiphene) | Erectile dysfunction (ED), Hair loss |
| Medication in price | Included | Extra |
| Drugs dispensed | FDA-approved | FDA-approved |
| Labs | Not stated | Free annual lab with Everyday Rx; labs in Skincare Rx |
| Membership | None found | Everyday Rx: $29 a month on an annual plan or $59 month to month. Skincare Rx: $59 a month. None for a single visit |
| Insurance | No (Rex MD does not accept insurance) | No, Sesame does not bill insurance; HSA and FSA funds can be used |
| States | All 50 states, per its own site (2026-10-31) | All 50 states, on its own statement |
| Cancellation | Pause or cancel any time; refunds case by case | Cancel a subscription any time before the next billing cycle; fees already paid are not refunded, except a full refund if cancelled 3 hours before the first visit |
| Trustpilot | 4.7/5 (5,269 reviews) | 4.6/5 (4,617 reviews) |
| Best for | Men who want FDA-approved generics at a low per-dose price with the consult included. | Men who want a prescription from a clinician they pick and are happy to fill it at a pharmacy. |
| Prices checked | 2026-11-07 | 2026-11-07 |
Price by treatment
The lowest all-in plan each publishes for the treatments both offer, with the page we read it on.
| Treatment | Rex MD | Sesame |
|---|---|---|
| Erectile dysfunction (ED) | No all-in price published | No all-in price published |
| Hair loss | $18/mo (reduced price with a 6-month order) source, 2026-11-05 | No all-in price published |
Rex MD: a closer look
LifeMD's men's brand: generic sildenafil from $1.80 a dose and finasteride from $18 a month, consult included.
In its favour
- Generic sildenafil from $1.80 a dose with the consult included
- FDA-approved generics and brands only
- Free consult and two-day shipping
To weigh
- Pages give conflicting per-dose and finasteride prices
- No monthly total published for ED packs
Sesame: a closer look
Video visits with medication paid at your pharmacy, or Everyday Rx from $29 a month with sildenafil and tadalafil at $1.
In its favour
- Choose your own clinician, with same-day visits
- Sildenafil and tadalafil at $1 on Everyday Rx
- Prescription can go to the pharmacy you choose
To weigh
- Medication is paid separately from the visit or subscription
- The lowest subscription price is an annual plan
- Pack size per $1 fill is not stated
Which should you choose?
Choose Rex MD
Best for men who want FDA-approved generics at a low per-dose price with the consult included. Its lowest all-in plan is $18/mo (reduced price with a 6-month order).
Check Rex MD's priceChoose Sesame
Best for men who want a prescription from a clinician they pick and are happy to fill it at a pharmacy.
Check Sesame's priceRex MD vs Sesame: questions people ask
Which is better, Rex MD or Sesame?
On our published score Rex MD rates 9.1 and Sesame rates 8.5. Rex MD is best for men who want FDA-approved generics at a low per-dose price with the consult included; Sesame is best for men who want a prescription from a clinician they pick and are happy to fill it at a pharmacy.
Do Rex MD and Sesame offer the same treatments?
Rex MD: Erectile dysfunction (ED), Hair loss, Premature ejaculation (PE), Low testosterone (TRT and enclomiphene). Sesame: Erectile dysfunction (ED), Hair loss.
Does either include the medication in the price?
Rex MD: included. Sesame: extra.
Men's Health Watchdog is for information only and is not medical advice. Sildenafil, tadalafil, finasteride, oral minoxidil and testosterone are prescription drugs (testosterone is a federally controlled substance); talk to a licensed clinician about whether one is right for you and at what dose. Compare other programs.