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SafetyUpdated November 14, 2026

Finasteride and Tamsulosin Together: What the Labels Say

Finasteride and tamsulosin for an enlarged prostate: how each works, what the labels say about taking both, side effects that add up, and what to tell a doctor.

By Julian Caraulani · Last updated

SafetyReviewed by Dr. A. Goher, MBBS

Quick answer
Finasteride and tamsulosin can be prescribed together for an enlarged prostate, and their labels show no harmful interaction between them. In lab tests, the Flomax label found "no evidence of clinically significant metabolic interactions between tamsulosin hydrochloride and" finasteride (DailyMed: Flomax label, revised January 2019, read 14 Nov 2026). The two work in different ways. Some side effects, mainly on ejaculation, can add up.
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This page sticks to label facts: what each drug does, what the labels say about using them together, and what to watch for. We do not give doses. The doctor treating your prostate decides the plan.

How finasteride and tamsulosin each work

An enlarged prostate, called benign prostatic hyperplasia or BPH, squeezes the tube that carries urine. Peeing gets slow, weak or frequent. The two drugs attack that problem from two sides.

Tamsulosin (Flomax) Finasteride (Proscar)
Drug class Alpha blocker 5-alpha reductase inhibitor
What it does Relaxes muscle in the prostate and bladder Blocks DHT, the hormone that makes the prostate grow
Main label warnings Dizziness on standing, eye surgery risk, rare long erections Lowers PSA, possible rise in high-grade prostate cancer, risk to a male baby
Source Flomax label, read 14 Nov 2026 Proscar label, revised 3/2026, read 14 Nov 2026

MedlinePlus describes tamsulosin simply: "It works by relaxing the muscles in the prostate and bladder so that urine can flow easily" (MedlinePlus: tamsulosin, read 14 Nov 2026). For finasteride, it says the drug "treats BPH by blocking the body's production of a male hormone that causes the prostate to enlarge" (MedlinePlus: finasteride). That hormone is DHT.

What the labels say about taking both

Neither label names the other drug in its approved uses. The Proscar label approves finasteride with a different alpha blocker, doxazosin: "PROSCAR administered in combination with the alpha-blocker doxazosin is indicated to reduce the risk of symptomatic progression of BPH" (DailyMed: Proscar label). Tamsulosin belongs to the same drug family as doxazosin. The finasteride and tamsulosin pair itself is not a labelled combination.

On interactions, the Flomax label reports lab work with liver enzymes. It found no sign that tamsulosin and finasteride change how the liver breaks each other down. The Proscar label adds that finasteride was used in its studies alongside "α-blockers" and other common drugs "without evidence of clinically significant adverse interactions" (DailyMed: Proscar label). Alpha blockers is the family name that covers tamsulosin.

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What the combination study found

The best data on finasteride plus an alpha blocker comes from the MTOPS study in the Proscar label. It followed 3,047 men with BPH for about five years. They were split into four groups: finasteride, doxazosin, both together, or a dummy pill (a placebo) for comparison.

Against the dummy pill, the risk of symptoms getting clearly worse "was reduced by 30%" with finasteride alone, 46% with doxazosin alone, and 64% with both (DailyMed: Proscar label). The label says the pair "significantly reduced the risk of symptom score progression compared to the effect of PROSCAR alone". That study used doxazosin, not tamsulosin, so treat it as a guide to the approach, not to your exact pills.

Side effects that can add up

The same study listed the side effects that were more common with both drugs than with either one. The label names "asthenia, postural hypotension, peripheral edema, dizziness, decreased libido, rhinitis, abnormal ejaculation, impotence and abnormal sexual function" (DailyMed: Proscar label). In plain words: weakness, a drop in blood pressure when you stand up, swollen ankles, dizziness, lower sex drive, a stuffy nose, ejaculation changes and erection trouble.

Ejaculation is the clearest overlap. Each drug affects it on its own:

Side effect Rate on the drug Rate on dummy pill Source
Abnormal ejaculation, tamsulosin (two strengths in US trials) 8.4% and 18.1% 0.2% Flomax label, Table 1
Ejaculation disorder, finasteride for hair loss 1.2% 0.7% Propecia label, Table 1

The Flomax label explains that abnormal ejaculation "includes ejaculation failure, ejaculation disorder, retrograde ejaculation, and ejaculation decrease". Retrograde ejaculation means semen goes back into the bladder instead of out.

Tamsulosin warnings to know

The Flomax label carries a few warnings that do not apply to finasteride, so they are new when you add tamsulosin.

  • Dizziness on standing. The label says signs of a blood pressure drop on standing "were detected more frequently in FLOMAX capsule-treated patients than in placebo recipients". Stand up slowly, especially at first.
  • Eye surgery. A problem called floppy iris syndrome "has been observed during cataract and glaucoma surgery in some patients on or previously treated with alpha 1 blockers, including FLOMAX capsules". Tell your eye surgeon you take or took it.
  • Long erections. Very rarely, tamsulosin "has been associated with priapism (persistent painful penile erection unrelated to sexual activity)". That needs urgent care.
  • Sulfa allergy. Men with a serious sulfa allergy should tell the prescriber.
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The PSA test: tell your doctor about finasteride

This one matters when you take both. Finasteride lowers PSA, the blood test used to screen for prostate cancer. The Proscar label says it "reduces serum prostate specific antigen (PSA) levels by approximately 50%" (DailyMed: Proscar label). The Flomax label, for its part, says "patients should be screened for the presence of prostate cancer prior to treatment with FLOMAX capsules and at regular intervals afterwards". Whoever reads your PSA result needs to know you take finasteride.

Alcohol with the pair

Finasteride has no alcohol warning on its label. Tamsulosin is different. The federal alcohol institute lists Flomax under enlarged prostate drugs, with "Dizziness, light headedness, fainting" as the risk when mixed with alcohol (NIAAA: Harmful Interactions, read 14 Nov 2026). Our finasteride and alcohol guide covers drinking on finasteride.

Combination capsules

MedlinePlus lists Jalyn as a combination product "containing Dutasteride, Tamsulosin" and notes "This branded product is no longer on the market" (MedlinePlus: tamsulosin). That capsule uses dutasteride, not finasteride. Entadfi is an approved capsule that pairs finasteride with tadalafil for BPH. Our tadalafil for BPH guide covers that drug. Our finasteride vs dutasteride guide compares the two hormone blockers.

Where online programs fit

The online programs we track sell finasteride for hair loss, not tamsulosin or finasteride for the prostate. Prostate care usually runs through your own doctor or a urologist. For hair loss, generic finasteride starts at $0.83 a tablet at Strut Health, as checked November 14, 2026. Every hair loss plan is on our finasteride price page, and the ranked programs are on Best men's health programs. If you already take finasteride for the prostate, do not add a hair loss plan on top without telling both prescribers.

Questions

FAQ

Can you take finasteride and tamsulosin together?

Yes, doctors can prescribe finasteride and tamsulosin together for an enlarged prostate. The Flomax label found no sign of a metabolic interaction between them in lab tests. The Proscar label approves finasteride with doxazosin, another drug from the same family as tamsulosin. Side effects on ejaculation, sex drive and dizziness can add up, so your doctor watches for them.

Why take finasteride and tamsulosin at the same time?

They do different jobs. Tamsulosin relaxes muscle in the prostate and bladder so urine flows more easily. Finasteride blocks DHT, the hormone that makes the prostate grow. In the label's MTOPS study, finasteride plus an alpha blocker cut the risk of symptoms getting worse more than either drug alone.

Does finasteride and tamsulosin cause erectile dysfunction?

Both can affect sex. In the MTOPS study, impotence, lower sex drive and ejaculation changes were more common with both drugs than with either one. Finasteride's hair loss trials found erectile dysfunction in 1.3% of men against 0.7% on a dummy pill. Tell your doctor about any change.

Can finasteride and tamsulosin cause dizziness?

Tamsulosin can. Its label warns that a drop in blood pressure on standing was more common than on a dummy pill, and the MTOPS combination group had more dizziness and low blood pressure on standing. Stand up slowly, and be careful with alcohol, which the NIAAA says adds to the risk with Flomax.

Is there one pill with finasteride and tamsulosin?

MedlinePlus lists Jalyn as a tamsulosin combination, but it holds dutasteride, not finasteride, and the brand is no longer on the market. Entadfi pairs finasteride with tadalafil instead. For finasteride with tamsulosin, men take two separate products.

Does tamsulosin affect the PSA test like finasteride does?

The Flomax label asks for prostate cancer screening before and during treatment. It is finasteride that lowers PSA, by about half according to the Proscar label. Whoever orders your PSA test needs to know you take finasteride, so the result can be read correctly. For every finasteride hair loss plan and price, see our finasteride cost page or the ranked list on Best men's health programs.

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