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SafetyUpdated November 14, 2026

Medications That Cause Hair Loss: What Each Drug Label Says

Medications that can cause hair loss, from each drug's own label: phentermine, Wellbutrin, Adderall, Accutane, Lexapro and metoprolol, plus what to do next.

By Julian Caraulani · Last updated

SafetyReviewed by Dr. A. Goher, MBBS

Quick answer
Some medications can cause hair loss, usually as shedding that stops after the drug does. MedlinePlus names "retinoids, birth control pills, beta-blockers, calcium channel blockers, certain antidepressants, NSAIDs (including ibuprofen)" (MedlinePlus: hair loss, read 14 Nov 2026). Below is what each common drug's label says. Never stop a medicine because of your hair without talking to the prescriber first.
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We read each label on DailyMed, the National Library of Medicine's library of official drug labels, on 14 Nov 2026. We do not give doses or medical advice. Your prescriber knows why you take the drug and what the options are.

First: do not stop the medicine on your own

The American Academy of Dermatology is blunt about this: "If you think a medication is causing your hair loss, ask the doctor who prescribed it if hair loss is a possible side effect. It's essential that you do not stop taking the medication before talking with your doctor. Abruptly stopping some medications can cause serious health problems" (AAD: 18 causes of hair loss, read 14 Nov 2026).

That matters most for heart and mood drugs. Stopping a beta-blocker or an antidepressant suddenly can cause real harm. The AAD also says hair can regrow once the cause is dealt with.

How drugs cause hair loss

Most drug-related hair loss is a type of shedding called telogen effluvium. Hair grows in cycles, and a drug can push many hairs into the resting stage at once. A few months later they fall out together. MedlinePlus lists medicines among the causes of this kind of shedding, and says "You may not notice this for weeks to months after the episode of stress." The same delay applies to a new drug.

So if your hair started falling out, think back two to four months. Was there a new prescription, a dose change, or a stop? Our diffuse thinning guide explains this shedding in more detail.

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What each label says

Labels list side effects from trials and from reports sent in after approval. Reports after approval cannot show how often a side effect happens or prove the drug caused it. Most labels say so. Still, a drug that lists hair loss is worth asking about.

Drug (brand) Used for Hair loss on its label? Source
Phentermine Short-term weight loss Not listed on the label we read Phentermine label
Bupropion (Wellbutrin XL) Depression, seasonal depression Yes, among reports after approval Wellbutrin XL label
Amphetamine salts (Adderall) ADHD, narcolepsy Yes, under skin side effects Adderall label
Isotretinoin (Absorica, once sold as Accutane) Severe acne Yes, and in some cases it lasted Absorica label
Escitalopram (Lexapro) Depression, anxiety Yes, among reports after approval Lexapro label
Metoprolol (Toprol-XL) Blood pressure, heart Yes, listed as reversible Toprol-XL label

Alopecia, the word labels use, is the medical term for hair loss.

Can phentermine cause hair loss?

The phentermine label we read lists side effects in the heart, nervous system, gut, allergy and hormone areas. It does not list hair loss (DailyMed: phentermine label).

If you shed while taking it, the more likely reason is the weight loss itself. The AAD lists having "Lost 20 pounds or more" among the triggers for excessive shedding (AAD: hair loss or shedding, read 14 Nov 2026). Fast weight loss from any cause, including diets low in protein, can do it. This kind of shedding usually settles within months.

Does Wellbutrin cause hair loss?

The Wellbutrin XL label lists it among skin reactions reported after approval: "Maculopapular rash, alopecia, angioedema, exfoliative dermatitis, hirsutism" (DailyMed: Wellbutrin XL label). The label notes these reports come from "a population of uncertain size", so the rate is unknown. Bupropion is the generic name.

Does Adderall cause hair loss?

The Adderall label lists alopecia under its skin side effects, in the same list as rashes and hives (DailyMed: Adderall label). It gives no rate. Adderall can also cut appetite and cause weight loss, which the label lists too, and weight loss can trigger shedding on its own.

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Does Accutane cause hair loss?

Yes, it is listed, and it is the one on this list where the label says it can last. Accutane was the original brand of isotretinoin; Absorica is a current brand. The label lists "alopecia(which in some cases persisted)" among skin side effects (DailyMed: Absorica label). Isotretinoin is a retinoid, a vitamin A drug, which MedlinePlus also names as a cause.

Does Lexapro cause hair loss?

The Lexapro label lists alopecia among reactions reported after approval: "alopecia, angioedema, dermatitis" sit at the start of its skin list (DailyMed: Lexapro label). Escitalopram is the generic name. MedlinePlus names "certain antidepressants" as a cause of shedding in general.

Can metoprolol cause hair loss?

The Toprol-XL label lists "reversible alopecia" among reactions reported after approval of Toprol-XL or the short-acting form of metoprolol (DailyMed: Toprol-XL label). Reversible means it went away. Metoprolol is a beta-blocker, a class MedlinePlus names. Never stop a beta-blocker suddenly; the label warns that stopping can worsen heart pain.

What to do if you think a drug is the cause

  1. Note the timing. When did the shedding start, and when did the drug start or change?
  2. Ask the prescriber. Bring this list. They may switch you to a similar drug, change the dose, or reassure you.
  3. Check other causes. The AAD lists thyroid disease and low iron, protein, zinc or biotin. A blood test can rule these out.
  4. Give it time. Drug-related shedding usually slows once the body adjusts or the drug changes. Hair grows back slowly, so fullness takes months.

When it is not the drug

Many men notice thinning while on a new medicine that would have happened anyway. Male pattern hair loss, which runs in families, can begin in the late teens or early twenties, the AAD says. If the thinning is at the temples and crown, and the back and sides stay thick, pattern loss is the more likely cause. The drug may just be bad timing.

Pattern loss does not stop on its own. Our male pattern baldness treatment guide covers finasteride and minoxidil, and our Norwood scale guide shows the usual stages.

What pattern hair loss treatment costs

Generic finasteride starts at $0.83 a tablet at Strut Health. The cheapest hair loss plan we track is Keeps at $14 a month, checked November 14, 2026. Every plan and its source is on our hair loss price page.

Questions

FAQ

What medications can cause hair loss?

Medications that can cause hair loss include retinoids such as isotretinoin, beta-blockers such as metoprolol, some antidepressants such as escitalopram and bupropion, amphetamines such as Adderall, birth control pills, calcium channel blockers and NSAIDs. Most cause shedding that stops once the body adjusts or the drug changes. Ask the prescriber before stopping anything.

Can phentermine cause hair loss?

The phentermine label we read does not list hair loss as a side effect. Shedding while on it is more likely caused by the weight loss itself. The AAD lists losing 20 pounds or more among the triggers for excessive shedding. This kind of shedding usually settles within months as weight steadies.

Does Wellbutrin cause hair loss?

The Wellbutrin XL label lists alopecia, the medical word for hair loss, among skin reactions reported after the drug was approved. Those reports come from a population of unknown size, so the label gives no rate. If you notice shedding, ask your prescriber. Do not stop an antidepressant suddenly on your own.

Does Adderall cause hair loss?

The Adderall label lists alopecia under skin side effects, with no rate given. Adderall can also reduce appetite and cause weight loss, and quick weight loss can trigger shedding on its own. Talk to the prescriber about timing and other causes before making any change.

Does Accutane cause hair loss?

Isotretinoin, first sold as Accutane, lists alopecia among skin side effects, and its label says that in some cases the hair loss persisted. That makes it the drug on this list with the clearest warning about lasting loss. Tell your dermatologist early if you notice shedding during a course.

Does Lexapro cause hair loss?

The Lexapro label lists alopecia among reactions reported after approval, with no rate given. MedlinePlus names certain antidepressants as a cause of shedding in general. Do not stop Lexapro suddenly; ask your prescriber about the timing, other causes, and whether a change makes sense.

Can metoprolol cause hair loss?

The Toprol-XL label lists reversible alopecia among reactions reported after approval of metoprolol. Reversible means the hair came back. Metoprolol is a beta-blocker, and stopping it suddenly can be dangerous for the heart. Ask your prescriber before any change. For pattern hair loss prices with their sources, see our hair loss cost page or the ranked list on Best men's health programs.

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