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TreatmentUpdated November 14, 2026

Testosterone and ED: Does TRT Help, and Can It Cause ED?

Testosterone and ED: what trials found on TRT and erections, why desire responds better than erections, whether TRT can cause ED, and what combined plans cost.

By Julian Caraulani · Last updated

TreatmentReviewed by Dr. A. Goher, MBBS

Quick answer
Testosterone and ED are linked, but less than many men expect. Low testosterone is one cause of erectile dysfunction, and testosterone therapy (TRT) can lift desire. For erections, the trials are mixed: in the largest, TRT "improved sexual activity, hypogonadal symptoms, and sexual desire, but not erectile function" (Pencina et al., J Clin Endocrinol Metab 2024, PubMed). Most men with ED still need an ED pill.
Top-rated partner for testosterone treatment
Strut Health
8.8/10Very good
From $79/mo, 30-day supply; tiers at $79, $99 and $119
  • FDA-approved and compounded
  • LegitScript seal ID shown
  • 49 states (not AR)

Below: how testosterone fits into ED, what three major trials found, whether TRT can cause ED, who should be tested, and what programs charge for TRT, ED pills or both. All sources were read on 14 November 2026. We list prices, never doses.

How testosterone and ED are connected

Erections depend on blood flow, nerves and hormones working together. The NIH lists "hormone issues, such as low testosterone and thyroid imbalance" among the most common causes of ED (NIDDK: Symptoms and causes of ED, read 14 November 2026). It lists heart and blood vessel disease, diabetes and medicines in the same breath.

So low testosterone is one cause among several, and often not the main one. Many men have both low testosterone and another cause, such as diabetes or narrowed arteries. That is why fixing the hormone alone often does not fix the erection.

Testosterone matters most for desire. Men with low testosterone often notice low interest in sex before they notice weaker erections. That difference shows up clearly in the trials below.

Does testosterone help erectile dysfunction?

Three large trials give the clearest answers. Their results differ, and the differences are worth knowing.

Trial Who took part What it found on erections Source
Testosterone Trials, 2016 790 men aged 65 and over with low testosterone Improved sexual activity, desire and erectile function; overall "a moderate benefit with respect to sexual function" Snyder et al., NEJM 2016
TRAVERSE sexual function study, 2024 1,161 men aged 45 to 80 with low testosterone and low desire Better sexual activity and desire, but not erectile function, over 2 years Pencina et al., JCEM 2024
Testosterone added to sildenafil, 2012 140 men aged 40 to 70 with ED and low testosterone, all on sildenafil Adding testosterone was no better than adding a dummy gel Spitzer et al., Ann Intern Med 2012

Read together, the picture is this. TRT tends to help desire and how often men have sex. Its effect on erections themselves is small or absent in the larger, longer trial.

Top-rated partner for testosterone treatment
Strut Health
8.8/10Very good
From $79/mo, 30-day supply; tiers at $79, $99 and $119
  • FDA-approved and compounded
  • LegitScript seal ID shown
  • 49 states (not AR)

The trial that tested testosterone on top of Viagra

The 2012 trial asked the question many men ask: if I already take sildenafil (Viagra), will adding testosterone help? All 140 men had their sildenafil adjusted first. Then half added a testosterone gel and half a dummy gel, chosen at random, for 14 weeks.

Sildenafil alone helped a lot. The study reports "Administration of sildenafil alone was associated with a substantial increase in EFD score", which is a standard erection score. Administration here simply means taking it. Adding testosterone did not add more: "Sildenafil plus testosterone was not superior to sildenafil plus placebo in improving erectile function in men with erectile dysfunction and low testosterone levels" (Spitzer et al., PubMed, read 14 November 2026). Placebo means a dummy gel with no hormone, the gel version of a dummy pill.

The authors note one limit: "Whether testosterone could improve erectile function without sildenafil was not studied."

What TRAVERSE found

TRAVERSE was a large trial built mainly to test heart safety. Inside it, a sexual function study followed 1,161 men with low testosterone and low desire for up to two years. They used a testosterone gel or a dummy gel, chosen at random.

Its conclusion: "In middle-aged and older men with hypogonadism and low libido, TRT for 2 years improved sexual activity, hypogonadal symptoms, and sexual desire, but not erectile function" (Pencina et al., PubMed, read 14 November 2026). Hypogonadism means the body makes too little testosterone. Libido means sex drive.

The older Testosterone Trials were more positive on erections. They found testosterone "associated with significantly increased sexual activity", with increased "sexual desire and erectile function" (Snyder et al., PubMed, read 14 November 2026). That trial lasted one year and enrolled men aged 65 and over.

What the NIH says about using both

The NIH's advice fits the trials. "If you have ED and low testosterone, health care professionals may prescribe testosterone with PDE5 inhibitors" (NIDDK: Treatment for ED, read 14 November 2026). PDE5 inhibitors are the ED pill family: sildenafil, tadalafil and others.

In practice, that means testosterone treats the low hormone and its symptoms, such as low desire and tiredness, while an ED pill treats the erection. Some programs sell both under one account; see TRT and ED from one program.

Ranked on safety and priceSee every men's health program side by side

Can TRT cause ED?

It is not a common effect on the labels. The AndroGel 1.62% label lists "decreased libido" among rare reports after the drug went on sale, and "libido decreased" among reactions in 2% of men or fewer in its trial (DailyMed: AndroGel 1.62% label, read 14 November 2026). The same postmarketing list includes "priapism (frequent or prolonged erections)", which is the opposite problem.

Two other label points often come up in the same conversation. Testosterone from outside the body can shrink sperm output: "spermatogenesis may be suppressed", meaning sperm making slows down. And "testicular atrophy", smaller testicles, is listed too. Neither is the same as ED, but both are reasons some men ask about enclomiphene instead; see enclomiphene vs TRT.

If erections get worse on TRT, the cause may be something else: the original cause of the ED, a new medicine, blood pressure, or stopping and starting treatment. Tell the prescriber; our TRT side effects guide covers the label warnings.

Can testosterone cause ED if you stop?

Stopping TRT lets testosterone fall back, often to where it started, and the symptoms that came with low testosterone can return. That can include low desire. Do not stop or change TRT without the prescriber, who can plan how to come off it.

Who should get tested first

TRT is approved for men with a real testosterone deficiency, not for ED alone. The AndroGel label says it is for "conditions associated with a deficiency or absence of endogenous testosterone", meaning the body's own testosterone. For men with low testosterone from aging alone, which the label calls age-related hypogonadism, it says safety and efficacy "have not been established". In plain words, nobody has shown how well or how safely it works for that group.

So the first step is a blood test. A man with ED and normal testosterone will not get an erection boost from TRT. A man with ED, low desire and low testosterone may benefit from both treatments. Our testosterone test cost guide prices the at-home and lab options.

What TRT, ED pills and combined plans cost

An ED pill is much cheaper than TRT. Generic sildenafil starts at $1.60 a dose at Strut Health, visit included. The cheapest all-in plan we list for low testosterone, TRT or enclomiphene, is $79 a month at Strut Health, as checked November 14, 2026. Many testosterone prices add a membership or first labs on top.

Two products pair testosterone support with tadalafil in one prescription. Both use enclomiphene, a pill that pushes the body to make more of its own testosterone, rather than testosterone itself.

Hims:

PlanWhat it isPer tabletPer monthBillingRead
Enclomiphene + tadalafil (Testosterone Rx+), plus membership
Enclomiphene with tadalafil (an ED drug) and supplements in one product. Whether it is compounded is not stated on the card.
Not statedNot published$49, plus add-onsplus the required $49 membershipNovember 6, 2026

Rugiet:

PlanWhat it isPer tabletPer monthBillingRead
Enclomiphene (Testosterone Rx, compounded)
Ongoing medically required labs included. The first labs cost $79, credited to the first order if you are approved. Rugiet sells enclomiphene, not testosterone itself.
Compounded, not FDA-approvedNot published$99monthly plans 'start at' this price; plan lengths only inside the intakeNovember 5, 2026
Enclomiphene + tadalafil (Enclomiphene+, compounded)
One product with tadalafil, an ED drug. Ongoing monitoring included; first labs $79, credited if approved.
Compounded, not FDA-approvedNot published$99monthly plans 'start at' this priceNovember 5, 2026

Every testosterone price is on our testosterone price page, programs are ranked on Best low testosterone programs, and ED programs on Best online ED programs.

Questions

FAQ

What is the link between testosterone and ED?

Low testosterone is one known cause of erectile dysfunction, alongside heart disease, diabetes, medicines and stress. It mostly lowers desire. In trials, testosterone therapy reliably raised desire and sexual activity, but its effect on erections was small or absent. Most men with ED and low testosterone are treated with an ED pill, sometimes alongside testosterone.

Does testosterone help erectile dysfunction?

Sometimes, a little. A 2016 trial in men over 65 found improved erectile function. The larger TRAVERSE study found better desire and sexual activity but not better erections over two years. A 2012 trial found adding testosterone to sildenafil was no better than adding a dummy gel.

Can TRT cause ED?

It is not a common effect. The AndroGel label lists decreased libido in a small share of men and, rarely, prolonged erections. Testosterone can reduce sperm output and testicle size, which are different problems. If erections get worse on TRT, look for another cause and tell the prescriber.

TRT and ED: can I take both treatments?

Yes, with a prescriber. The NIH says clinicians may prescribe testosterone together with an ED pill for men with ED and low testosterone. Several programs sell both under one account, priced separately. A blood test should confirm low testosterone before TRT starts.

Can testosterone cause ED if levels go too high?

The labels do not list ED as a result of high testosterone. They list rare prolonged erections, raised blood counts and higher blood pressure, which is why programs check blood work during treatment. Tell your prescriber about any change in erections, high or low, after starting.

Should I check my testosterone if I have ED?

It is a reasonable part of an ED work-up, especially with low desire or tiredness. The NIH notes clinicians may use blood tests when looking for the cause of ED. Normal testosterone means TRT will not help your erections, and an ED pill is the usual first step.

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